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Randomized trial · measured other health measures

8-week trial in 50 sports-training adults: better fitness and recovery scores with ashwagandha

Tiwari and colleagues · Journal of ethnopharmacology · 2021

Original title: A double-blind, randomized, placebo-controlled trial on the effect of Ashwagandha (Withania somnifera dunal.) root extract in improving cardiorespiratory endurance and recovery in healthy athletic adults.

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What the study found

Points to benefit

Fitness (VO2 max) rose more with ashwagandha than placebo (P = 0.0074). Recovery and stress-for-athletes questionnaires also scored better (P < 0.0001).

The study at a glance

Type of study
Randomized trial
Who or what was studied
50 people · healthy adults who train in sports
What was tested
300 mg of ashwagandha root extract twice a day for 8 weeks, vs placebo
What it measured
Several kinds of outcomes
Daily amount
600 mg a day
How long
8 weeks
Who has a stake
No disclosure in PubMed
No disclosure in PubMed.
Journal
Journal of ethnopharmacology, 2021
Source
PubMed record 33600918. This page is based on the abstract only.

How much this study counts

  • ✓Randomized: people were put into groups by chance, so the groups start out alike.
  • ✓Compared with a placebo, a dummy treatment.
  • •Medium size: 50 people.
  • –Short: 8 weeks. Longer-term effects are unknown.
  • •Measured several kinds of outcomes.
  • •The PubMed record has no conflict-of-interest statement.
  • •Summarized from the PubMed abstract only. The full paper may hold details the abstract leaves out.

✓ Strength– Limit• Note

These points come from fixed rules about the type of study, its size and length, what it measured, and who has a stake. Every study on Digestery gets the same rules.

Where this study sits

Each dot is one on-topic paper on this question. Steps near the top answer the question more directly.

↑ Stronger evidence

  1. Trials in people: stress and anxiety

    9

    7 benefit, 2 no difference

  2. Trials in people: other measures

    6

    3 benefit, 1 mixed, 1 no difference, 1 no direction

    ↑ This study is the ringed dot
  3. Trials in people: lab tests or safety

    1

    1 benefit

  4. Population studies

    1

    1 benefit

  5. Blood levels and genes

    0

    None among the papers we read.

↓ Weaker evidence

  • Points to benefit
  • Mixed
  • No difference
  • No direction
  • Points to harm

How it fits with the other research

The short answer to “Does ashwagandha reduce stress and anxiety?”

Possibly, but the evidence is weak.

Confidence: low. Based on 24 on-topic papers.

Read the full answer

Of the other 4 papers on the same step: 2 benefit, 1 mixed, 1 no difference. This one found benefit.

Other papers on the same step

See all 24 studies on this question

How this page was made

Label

First read of the abstract
Claude Sonnet
Independent second read
Claude Haiku
Differences settled
The reviewer corrected 2 fields after reading the abstract. Claude Opus 5.5.
Headline
Claude Sonnet, from the checked study record. A script checked its numbers and wording.
Numbers
Checked against the abstract by a script
“How much this study counts”
Fixed rules, the same for every study
Source check by a person
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