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Randomized trial · measured other health measures

Trial in older adults with broken hips: taurine did not clearly change outcomes

Van Stijn and colleagues · International journal of molecular sciences · 2015

Original title: Effect of oral taurine on morbidity and mortality in elderly hip fracture patients: a randomized trial.

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What the study found

No difference

Taurine did not improve complications in hospital, illness in the first year, or deaths in the first year. It lowered a stress marker in urine (8-hydroxy-2-deoxyguanosine; Beta: -0.54; 95% CI: -1.08--0.01; p = 0.04).

The study at a glance

Type of study
Randomized trial
Who or what was studied
elderly people with a broken hip waiting for surgery
What was tested
Taurine by mouth from admission to day 6 after surgery, vs placebo; followed for 1 year
What it measured
Several kinds of outcomes
How long
1 week
Who has a stake
No disclosure in PubMed
No disclosure in PubMed.
Journal
International journal of molecular sciences, 2015
Source
PubMed record 26035756. This page is based on the abstract only.

How much this study counts

  • ✓Randomized: people were put into groups by chance, so the groups start out alike.
  • ✓Compared with a placebo, a dummy treatment.
  • •The abstract does not say how many people took part.
  • –Short: 1 week. Longer-term effects are unknown.
  • •Measured several kinds of outcomes.
  • •The PubMed record has no conflict-of-interest statement.
  • •Summarized from the PubMed abstract only. The full paper may hold details the abstract leaves out.

✓ Strength– Limit• Note

These points come from fixed rules about the type of study, its size and length, what it measured, and who has a stake. Every study on Digestery gets the same rules.

Where this study sits

Each dot is one on-topic paper on this question. Steps near the top answer the question more directly.

↑ Stronger evidence

  1. Trials in people: aging and age-related decline

    1

    1 benefit

  2. Trials in people: other measures

    3

    1 benefit, 1 mixed, 1 no difference

    ↑ This study is the ringed dot

  3. Trials in people: lab tests or safety

    2

    2 benefit

  4. Population studies

    2

    1 no difference, 1 harm

  5. Blood levels and genes

    2

    1 mixed, 1 no direction

  6. Animals

    2

    1 benefit, 1 no difference

  7. Cells in a dish

    1

    1 benefit

↓ Weaker evidence

  • Points to benefit
  • Mixed
  • No difference
  • No direction
  • Points to harm

How it fits with the other research

The short answer to “Does taurine slow aging?”

Not shown in people.

Confidence: very low. Based on 13 on-topic papers.

Read the full answer

Of the other 2 papers on the same step: 1 benefit, 1 mixed. This one found no difference.

Other papers on the same step

See all 13 studies on this question

How this page was made

Label

First read of the abstract
Claude Sonnet
Independent second read
Claude Haiku
Differences settled
The reviewer corrected 1 field after reading the abstract. Claude Opus 5.5.
Headline
Claude Sonnet, from the checked study record. A script checked its numbers and wording.
Numbers
Checked against the abstract by a script
“How much this study counts”
Fixed rules, the same for every study
Source check by a person
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