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Longevity supplements › Taurine and Aging › Studies

Randomized trial · measured other health measures

14-week trial in 48 women aged about 84: taurine and exercise gave mixed results

Chupel and colleagues · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2018

Original title: Exercise and taurine in inflammation, cognition, and peripheral markers of blood-brain barrier integrity in older women.

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What the study found

Mixed

Taurine alone lowered one inflammation ratio (IL-1β/IL-1ra) and raised NSE, a blood marker of blood-brain barrier integrity (p < 0.05). Memory score (MMSE) rose only in the exercise plus taurine group (p < 0.05).

The study at a glance

Type of study
Randomized trial
Who or what was studied
48 people · women aged about 84 (average 83.58)
What was tested
1.5 g of taurine a day, exercise twice a week, both together, or neither, for 14 weeks
What it measured
Several kinds of outcomes
Daily amount
1.5 g a day
How long
14 weeks
Who has a stake
No disclosure in PubMed
No disclosure in PubMed.
Journal
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2018
Source
PubMed record 29474803. This page is based on the abstract only.

How much this study counts

  • ✓Randomized: people were put into groups by chance, so the groups start out alike.
  • –Small: 48 people. Small trials can miss real effects or find chance ones.
  • •Lasted 14 weeks.
  • •Measured several kinds of outcomes.
  • •The PubMed record has no conflict-of-interest statement.
  • •Summarized from the PubMed abstract only. The full paper may hold details the abstract leaves out.

✓ Strength– Limit• Note

These points come from fixed rules about the type of study, its size and length, what it measured, and who has a stake. Every study on Digestery gets the same rules.

Where this study sits

Each dot is one on-topic paper on this question. Steps near the top answer the question more directly.

↑ Stronger evidence

  1. Trials in people: aging and age-related decline

    1

    1 benefit

  2. Trials in people: other measures

    3

    1 benefit, 1 mixed, 1 no difference

    ↑ This study is the ringed dot

  3. Trials in people: lab tests or safety

    2

    2 benefit

  4. Population studies

    2

    1 no difference, 1 harm

  5. Blood levels and genes

    2

    1 mixed, 1 no direction

  6. Animals

    2

    1 benefit, 1 no difference

  7. Cells in a dish

    1

    1 benefit

↓ Weaker evidence

  • Points to benefit
  • Mixed
  • No difference
  • No direction
  • Points to harm

How it fits with the other research

The short answer to “Does taurine slow aging?”

Not shown in people.

Confidence: very low. Based on 13 on-topic papers.

Read the full answer

Of the other 2 papers on the same step: 1 benefit, 1 no difference. This one found mixed.

Other papers on the same step

See all 13 studies on this question

How this page was made

Label

First read of the abstract
Claude Sonnet
Independent second read
Claude Haiku
Differences settled
The reviewer corrected 1 field after reading the abstract. Claude Opus 5.5.
Headline
Claude Sonnet, from the checked study record. A script checked its numbers and wording.
Numbers
Checked against the abstract by a script
“How much this study counts”
Fixed rules, the same for every study
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