Digestery
Diet and food › Moderate Drinking and the Heart › Studies

Opinion or narrative review

Review of wine and heart disease: benefits in some studies, doubts from gene studies

Martínez-González · The American journal of clinical nutrition · 2024

Original title: Should we remove wine from the Mediterranean diet?: a narrative review.

Under review. A person has not yet checked this summary against the paper. It is written from the PubMed abstract. Until a person checks it, search engines are asked not to list this page.

What the study found

Mixed

Non-randomized studies link light to moderate drinking to lower heart disease and death. But alcohol raises cancer and other risks, and gene studies suggest zero is healthiest. A 10,000-person trial (UNATI) is planned.

The study at a glance

Type of study
Opinion or narrative review
Who or what was studied
adults, from studies of wine and the Mediterranean diet
What was tested
Review of light to moderate alcohol or red wine and heart disease and death
Trial registration
NCT02669602
Who has a stake
No disclosure in PubMed
No disclosure in PubMed.
Journal
The American journal of clinical nutrition, 2024
Source
PubMed record 38157987. This page is based on the abstract only.

How much this study counts

  • –An opinion or narrative review: no new data, and no set method for choosing which studies to discuss.
  • •The PubMed record has no conflict-of-interest statement.
  • •Summarized from the PubMed abstract only. The full paper may hold details the abstract leaves out.

✓ Strength– Limit• Note

These points come from fixed rules about the type of study, its size and length, what it measured, and who has a stake. Every study on Digestery gets the same rules.

Where this study sits

This paper is not on the ladder. It is a opinion or narrative review, and reviews and opinion pieces discuss studies that are already counted on the steps below.

↑ Stronger evidence

  1. Trials in people: heart disease

    0

    Not done yet. This is the step that would answer the question.

  2. Trials in people: other measures

    0

    None among the papers we read.

  3. Trials in people: lab tests or safety

    0

    None among the papers we read.

  4. Population studies

    5

    3 benefit, 1 mixed, 1 harm

  5. Blood levels and genes

    6

    1 mixed, 2 no difference, 3 harm

↓ Weaker evidence

  • Points to benefit
  • Mixed
  • No difference
  • No direction
  • Points to harm

How it fits with the other research

The short answer to “Is moderate drinking good or bad for your heart?”

Not shown to help; may harm.

Confidence: very low. Based on 21 on-topic papers.

Read the full answer
  • Quoted in “What we found”: No long-term trial has tested drinking against heart events. A Spanish trial planned to randomly assign more than 10,000 drinkers to quitting or moderation advice.
  • On the watch list: UNATI: a trial of drinking advice.

Other opinion on this question

See all 21 studies on this question

How this page was made

Label

First read of the abstract
Claude Sonnet
Independent second read
Claude Haiku
Differences settled
The two reads differed. The reviewer checked the abstract and kept the first read. Claude Opus 5.5.
Headline
Claude Sonnet, from the checked study record. A script checked its numbers and wording.
Numbers
Checked against the abstract by a script
“How much this study counts”
Fixed rules, the same for every study
Source check by a person
Not yet. Required before search engines may list this page.

Spot an error? Email a flag with a link to your source, or use the form on the question page.