Every study we read on this question

Population studies (1)

• Blood-test study of adults: fewer worn-out cells went with fisetin use in small subgroup
  Population study: one-time survey2024Points to benefit

Animal and cell (6)

• In obese mice, fisetin cut worn-out cells in fat and improved blood sugar handling
  Animal study2025Points to benefit
• In old mice, clearing worn-out heart cells, fisetin included, lowered one immune cell type
  Animal study2025Points to benefit
• In mice with kidney damage from a cancer drug, fisetin and ABT-263 reduced scarring
  Animal study2023Points to benefit
• In mice with muscular dystrophy, 4 weeks of fisetin improved muscle traits
  Animal study2022Points to benefit
• In lupus mice, fisetin lowered worn-out brain cells and depression-like behavior
  Animal study2021Points to benefit
• In lab-grown cells, fisetin killed worn-out mouse cells but not worn-out human skin-cancer cells
  Cell study2023Mixed

Reviews (2)

• Review of 13 cell and animal studies: fisetin helped bone loss, no human data
  Systematic review2022Points to benefit
• Review of three food compounds, fisetin among them, in Alzheimer's disease: authors say helpful
  Systematic review2020Points to benefit

Opinion (3)

• Herbal mix study: in lab-grown ovary cells, fisetin and quercetin lowered cell-aging markers
  Other2026Points to benefit
• Review of four natural compounds including fisetin and how they act on aging pathways
  Opinion or narrative review2026No direction
• Opinion piece on how fisetin and quercetin may kill worn-out cells
  Opinion or narrative review2021No direction