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Trial, not randomized · measured other health measures

5-day trial in 60 adults after heart surgery: magnesium gave better sleep scores

Saba and colleagues · Magnesium research · 2022

Original title: Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.

Under review. A person has not yet checked this summary against the paper. It is written from the PubMed abstract. Until a person checks it, search engines are asked not to list this page.

What the study found

Points to benefit

Sleep score (lower is better) was 8.3 ± 2.1 with magnesium vs 10.3 ± 2.0 in usual care (p=0.001). Anxiety and depression were also lower (p=0.007).

The study at a glance

Type of study
Trial, not randomized
Who or what was studied
60 people · 60 adults after open-heart surgery
What was tested
500 mg magnesium oxide a day for 5 days vs usual care only
What it measured
Several kinds of outcomes
Daily amount
500 mg a day
How long
1 week
Who has a stake
No disclosure in PubMed
No disclosure in PubMed.
Journal
Magnesium research, 2022
Source
PubMed record 36354243. This page is based on the abstract only.

How much this study counts

  • –Not randomized: the groups may differ in ways that affect the result.
  • •Medium size: 60 people.
  • –Short: 1 week. Longer-term effects are unknown.
  • •Measured several kinds of outcomes.
  • •The PubMed record has no conflict-of-interest statement.
  • •Summarized from the PubMed abstract only. The full paper may hold details the abstract leaves out.

✓ Strength– Limit• Note

These points come from fixed rules about the type of study, its size and length, what it measured, and who has a stake. Every study on Digestery gets the same rules.

Where this study sits

Each dot is one on-topic paper on this question. Steps near the top answer the question more directly.

↑ Stronger evidence

  1. Trials in people: sleep quality and insomnia

    1

    1 benefit

  2. Trials in people: other measures

    6

    4 benefit, 2 no difference

    ↑ This study is the ringed dot

  3. Trials in people: lab tests or safety

    0

    None among the papers we read.

  4. Population studies

    3

    2 mixed, 1 no difference

  5. Blood levels and genes

    3

    2 benefit, 1 no difference

↓ Weaker evidence

  • Points to benefit
  • Mixed
  • No difference
  • No direction
  • Points to harm

How it fits with the other research

The short answer to “Does magnesium help you sleep?”

Not clearly; trials disagree.

Confidence: very low. Based on 16 on-topic papers.

Read the full answer

Of the other 5 papers on the same step: 3 benefit, 2 no difference. This one found benefit. It agrees with most of them.

Other papers on the same step

See all 16 studies on this question

How this page was made

Label

First read of the abstract
Claude Sonnet
Independent second read
Claude Haiku
Differences settled
The two reads differed. The reviewer checked the abstract and kept the first read. Claude Opus 5.5.
Headline
Claude Sonnet, from the checked study record. A script checked its numbers and wording.
Numbers
Checked against the abstract by a script
“How much this study counts”
Fixed rules, the same for every study
Source check by a person
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