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Blood level study

Study of 82 adults with fibromyalgia: poor sleep went with lower blood magnesium

Alisik and colleagues · Medicine · 2025

Original title: Serum magnesium levels and their association with sleep quality and disease severity in fibromyalgia syndrome: An observational cross-sectional study.

Under review. A person has not yet checked this summary against the paper. It is written from the PubMed abstract. Until a person checks it, search engines are asked not to list this page.

What the study found

Points to benefit

The poor-sleep group had lower blood magnesium (P = .038). Magnesium and sleep scores were negatively correlated (ρ = -0.324, P = .003). Cause cannot be shown.

The study at a glance

Type of study
Blood level study
Who or what was studied
82 people · 82 adults with fibromyalgia (a long-term pain condition)
What was tested
Compared blood magnesium in people with poor sleep (PSQI > 5, 55 people) and good sleep (27 people)
What it measured
The question itself: sleep quality and insomnia
Who has a stake
No stake declared
No competing interests declared.
Journal
Medicine, 2025
Source
PubMed record 40696633. This page is based on the abstract only.

How much this study counts

  • –Links blood levels to health. A blood level can be a sign of illness rather than a cause.
  • •82 people.
  • ✓Measured the question itself: sleep quality and insomnia.
  • ✓No competing interests declared.
  • •Summarized from the PubMed abstract only. The full paper may hold details the abstract leaves out.

✓ Strength– Limit• Note

These points come from fixed rules about the type of study, its size and length, what it measured, and who has a stake. Every study on Digestery gets the same rules.

Where this study sits

Each dot is one on-topic paper on this question. Steps near the top answer the question more directly.

↑ Stronger evidence

  1. Trials in people: sleep quality and insomnia

    1

    1 benefit

  2. Trials in people: other measures

    6

    4 benefit, 2 no difference

  3. Trials in people: lab tests or safety

    0

    None among the papers we read.

  4. Population studies

    3

    2 mixed, 1 no difference

  5. Blood levels and genes

    3

    2 benefit, 1 no difference

    ↑ This study is the ringed dot

↓ Weaker evidence

  • Points to benefit
  • Mixed
  • No difference
  • No direction
  • Points to harm

How it fits with the other research

The short answer to “Does magnesium help you sleep?”

Not clearly; trials disagree.

Confidence: very low. Based on 16 on-topic papers.

Read the full answer

Of the other 2 papers on the same step: 1 benefit, 1 no difference. This one found benefit.

Other papers on the same step

See all 16 studies on this question

How this page was made

Label

First read of the abstract
Claude Sonnet
Independent second read
Claude Haiku
Differences settled
The reviewer corrected 1 field after reading the abstract. Claude Opus 5.5.
Headline
Claude Sonnet, from the checked study record. A script checked its numbers and wording.
Numbers
Checked against the abstract by a script
“How much this study counts”
Fixed rules, the same for every study
Source check by a person
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