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Randomized trial · measured the question itself

3-month trial in 99 adults with diabetes: 16:8 and 14:10 fasting lost more weight

Sukkriang and colleagues · Journal of diabetes investigation · 2024

Original title: Effect of intermittent fasting 16:8 and 14:10 compared with control-group on weight reduction and metabolic outcomes in obesity with type 2 diabetes patients: A randomized controlled trial.

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What the study found

Points to benefit

Weight change was -4.02% with 16:8, -3.15% with 14:10 and -0.55% in controls (P < 0.001 for both fasting groups vs controls). 16:8 lost more than 14:10 (P < 0.001).

The study at a glance

Type of study
Randomized trial
Who or what was studied
99 people · adults with obesity and type 2 diabetes
What was tested
16:8 or 14:10 fasting, 3 days a week for 3 months, vs normal controlled diet
What it measured
The question itself: weight loss, compared with ordinary calorie cutting
How long
12 weeks
Who has a stake
No stake declared
No conflicts of interest to disclose.
Journal
Journal of diabetes investigation, 2024
Source
PubMed record 38932663. This page is based on the abstract only.

How much this study counts

  • ✓Randomized: people were put into groups by chance, so the groups start out alike.
  • •Medium size: 99 people.
  • •Lasted 12 weeks.
  • ✓Measured the question itself: weight loss, compared with ordinary calorie cutting.
  • ✓No competing interests declared.
  • •Summarized from the PubMed abstract only. The full paper may hold details the abstract leaves out.

✓ Strength– Limit• Note

These points come from fixed rules about the type of study, its size and length, what it measured, and who has a stake. Every study on Digestery gets the same rules.

Where this study sits

Each dot is one on-topic paper on this question. Steps near the top answer the question more directly.

↑ Stronger evidence

  1. Trials in people: weight loss

    9

    5 benefit, 2 mixed, 2 no difference

    ↑ This study is the ringed dot

  2. Trials in people: other measures

    8

    4 benefit, 3 mixed, 1 no difference

  3. Trials in people: lab tests or safety

    1

    1 benefit

  4. Population studies

    0

    None among the papers we read.

  5. Blood levels and genes

    0

    None among the papers we read.

↓ Weaker evidence

  • Points to benefit
  • Mixed
  • No difference
  • No direction
  • Points to harm

How it fits with the other research

The short answer to “Does intermittent fasting help with weight loss?”

Yes, but about like calorie cutting.

Confidence: moderate. Based on 26 on-topic papers.

Read the full answer

Of the other 8 papers on the same step: 4 benefit, 2 mixed, 2 no difference. This one found benefit.

  • Open item for a person: Sukkriang 2024 cites Thai registry TCTR 20230131002 in its disclosures but has no trial registration field.

Other papers on the same step

See all 26 studies on this question

How this page was made

Label

First read of the abstract
Claude Sonnet
Independent second read
Claude Haiku
Differences settled
The two reads agreed on every checked field. Claude Opus 5.5.
Headline
Claude Sonnet, from the checked study record. A script checked its numbers and wording.
Numbers
Checked against the abstract by a script
“How much this study counts”
Fixed rules, the same for every study
Source check by a person
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