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Population study: followed a group

In 500,705 US adults, aerobic plus muscle-strengthening activity linked to lowest death risk

López-Bueno and colleagues · JAMA internal medicine · 2023

Original title: Prospective Associations of Different Combinations of Aerobic and Muscle-Strengthening Activity With All-Cause, Cardiovascular, and Cancer Mortality.

Under review. A person has not yet checked this summary against the paper. It is written from the PubMed abstract. Until a person checks it, search engines are asked not to list this page.

What the study found

Points to benefit

Lowest all-cause death risk (HR, 0.50; 95% CI, 0.42-0.59) was for some moderate aerobic, more than 150 minutes of vigorous aerobic and 2 or more muscle-strengthening sessions a week. Muscle strengthening alone is not isolated in the abstract.

The study at a glance

Type of study
Population study: followed a group
Who or what was studied
500,705 people · US adults in a national health survey, mean age 46.4, followed a median 10.0 years
What was tested
48 mixes of moderate aerobic, vigorous aerobic and muscle-strengthening activity (2 or more sessions a week or not), vs no aerobic and less muscle strengthening than recommended
What it measured
The question itself: death from any cause and healthy aging
Who has a stake
No stake declared
Authors report only public research support; no company tie.
Journal
JAMA internal medicine, 2023
Source
PubMed record 37548973. This page is based on the abstract only.

How much this study counts

  • –Shows a link, not a cause: people chose their own habits, and other differences between them may explain the result.
  • ✓Followed people over time, so habits were recorded before the outcome happened.
  • ✓Large: 500,705 people.
  • ✓Measured the question itself: death from any cause and healthy aging.
  • ✓No competing interests declared.
  • •Summarized from the PubMed abstract only. The full paper may hold details the abstract leaves out.

✓ Strength– Limit• Note

These points come from fixed rules about the type of study, its size and length, what it measured, and who has a stake. Every study on Digestery gets the same rules.

Where this study sits

Each dot is one on-topic paper on this question. Steps near the top answer the question more directly.

↑ Stronger evidence

  1. Trials in people: death and healthy aging

    0

    Not done yet. This is the step that would answer the question.

  2. Trials in people: other measures

    9

    7 benefit, 2 no difference

  3. Trials in people: lab tests or safety

    0

    None among the papers we read.

  4. Population studies

    9

    8 benefit, 1 mixed

    ↑ This study is the ringed dot

  5. Blood levels and genes

    0

    None among the papers we read.

↓ Weaker evidence

  • Points to benefit
  • Mixed
  • No difference
  • No direction
  • Points to harm

How it fits with the other research

The short answer to “Does strength training help you live longer?”

Linked to longer life; not proven.

Confidence: low. Based on 26 on-topic papers.

Read the full answer

Of the other 8 papers on the same step: 7 benefit, 1 mixed. This one found benefit. It agrees with most of them.

Other papers on the same step

See all 26 studies on this question

How this page was made

Label

First read of the abstract
Claude Sonnet
Independent second read
Claude Haiku
Differences settled
The two reads agreed on every checked field. Claude Opus 5.5.
Headline
Claude Sonnet, from the checked study record. A script checked its numbers and wording.
Numbers
Checked against the abstract by a script
“How much this study counts”
Fixed rules, the same for every study
Source check by a person
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