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Randomized trial · measured other health measures

Trial in 112 intensive care patients: resistance exercise improved physical performance and walking distance

Wu and colleagues · Critical care (London, England) · 2023

Original title: Effects of a multilevel intervention of resistance training with or without beta-hydroxy-beta-methylbutyrate in medical ICU patients during entire hospitalisation: a four-arm multicentre randomised controlled trial.

Under review. A person has not yet checked this summary against the paper. It is written from the PubMed abstract. Until a person checks it, search engines are asked not to list this page.

What the study found

Points to benefit

Resistance training raised the SPPB score by 3.848 points and 6-minute walk by 99.768 m vs control. No clear change in 60-day mortality, muscle mass or quality of life.

The study at a glance

Type of study
Randomized trial
Who or what was studied
112 people · adult patients in a medical intensive care unit
What was tested
Resistance exercise, or 3 g/day HMB supplement, or both, vs standard care, until hospital discharge
What it measured
Other health or performance measures
Trial registration
ChiCTR2200057685
Who has a stake
No stake declared
No competing interests declared.
Journal
Critical care (London, England), 2023
Source
PubMed record 38102705. This page is based on the abstract only.

How much this study counts

  • ✓Randomized: people were put into groups by chance, so the groups start out alike.
  • •Medium size: 112 people.
  • •Measured other health measures, not death from any cause and healthy aging itself.
  • ✓No competing interests declared.
  • •Summarized from the PubMed abstract only. The full paper may hold details the abstract leaves out.

✓ Strength– Limit• Note

These points come from fixed rules about the type of study, its size and length, what it measured, and who has a stake. Every study on Digestery gets the same rules.

Where this study sits

Each dot is one on-topic paper on this question. Steps near the top answer the question more directly.

↑ Stronger evidence

  1. Trials in people: death and healthy aging

    0

    Not done yet. This is the step that would answer the question.

  2. Trials in people: other measures

    9

    7 benefit, 2 no difference

    ↑ This study is the ringed dot

  3. Trials in people: lab tests or safety

    0

    None among the papers we read.

  4. Population studies

    9

    8 benefit, 1 mixed

  5. Blood levels and genes

    0

    None among the papers we read.

↓ Weaker evidence

  • Points to benefit
  • Mixed
  • No difference
  • No direction
  • Points to harm

How it fits with the other research

The short answer to “Does strength training help you live longer?”

Linked to longer life; not proven.

Confidence: low. Based on 26 on-topic papers.

Read the full answer

Of the other 8 papers on the same step: 6 benefit, 2 no difference. This one found benefit. It agrees with most of them.

Other papers on the same step

See all 26 studies on this question

How this page was made

Label

First read of the abstract
Claude Sonnet
Independent second read
Claude Haiku
Differences settled
The reviewer corrected 3 fields after reading the abstract. Claude Opus 5.5.
Headline
Claude Sonnet, from the checked study record. A script checked its numbers and wording.
Numbers
Checked against the abstract by a script
“How much this study counts”
Fixed rules, the same for every study
Source check by a person
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