Digestery
Everyday supplements › Collagen and Skin › Studies

Randomized trial · measured other health measures

Two trials of collagen peptides, up to 12 weeks: better skin hydration and density

Asserin and colleagues · Journal of cosmetic dermatology · 2015

Original title: The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials.

Under review. A person has not yet checked this summary against the paper. It is written from the PubMed abstract. Until a person checks it, search engines are asked not to list this page.

What the study found

Points to benefit

Skin hydration rose after 8 weeks of collagen peptides. Collagen density in the deep skin layer rose and collagen breakup fell after 4 weeks. Effects lasted to 12 weeks.

The study at a glance

Type of study
Randomized trial
Who or what was studied
Adults in two placebo-controlled trials, plus lab tests on skin samples
What was tested
Daily collagen peptides by mouth vs placebo, up to 12 weeks
What it measured
Several kinds of outcomes
How long
12 weeks
Who has a stake
No disclosure in PubMed
No disclosure in PubMed.
Journal
Journal of cosmetic dermatology, 2015
Source
PubMed record 26362110. This page is based on the abstract only.

How much this study counts

  • ✓Randomized: people were put into groups by chance, so the groups start out alike.
  • ✓Compared with a placebo, a dummy treatment.
  • •The abstract does not say how many people took part.
  • •Lasted 12 weeks.
  • •Measured several kinds of outcomes.
  • •The PubMed record has no conflict-of-interest statement.
  • •Summarized from the PubMed abstract only. The full paper may hold details the abstract leaves out.

✓ Strength– Limit• Note

These points come from fixed rules about the type of study, its size and length, what it measured, and who has a stake. Every study on Digestery gets the same rules.

Where this study sits

Each dot is one on-topic paper on this question. Steps near the top answer the question more directly.

↑ Stronger evidence

  1. Trials in people: wrinkles, skin elasticity and moisture

    15

    13 benefit, 2 mixed

  2. Trials in people: other measures

    1

    1 benefit

    ↑ This study is the ringed dot

  3. Trials in people: lab tests or safety

    0

    None among the papers we read.

  4. Population studies

    0

    None among the papers we read.

  5. Blood levels and genes

    0

    None among the papers we read.

↓ Weaker evidence

  • Points to benefit
  • Mixed
  • No difference
  • No direction
  • Points to harm

How it fits with the other research

The short answer to “Does collagen reduce skin aging?”

Unclear; higher-quality trials found no effect.

Confidence: low. Based on 22 on-topic papers.

Read the full answer

Few other papers sit on the same step, so there is little to compare it with.

Other papers on the same step

None among the papers we read.

See all 22 studies on this question

How this page was made

Label

First read of the abstract
Claude Sonnet
Independent second read
Claude Haiku
Differences settled
The reviewer corrected 1 field after reading the abstract. Claude Opus 5.5.
Headline
Claude Sonnet, from the checked study record. A script checked its numbers and wording.
Numbers
Checked against the abstract by a script
“How much this study counts”
Fixed rules, the same for every study
Source check by a person
Not yet. Required before search engines may list this page.

Spot an error? Email a flag with a link to your source, or use the form on the question page.