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Systematic review

Review of 11 trials, 805 people: collagen linked to higher skin elasticity and hydration

Choi and colleagues · Journal of drugs in dermatology : JDD · 2019

Original title: Oral Collagen Supplementation: A Systematic Review of Dermatological Applications.

Under review. A person has not yet checked this summary against the paper. It is written from the PubMed abstract. Until a person checks it, search engines are asked not to list this page.

What the study found

Points to benefit

Eleven studies with 805 patients were reviewed. Collagen was linked to higher skin elasticity, hydration and dermal collagen density. No side effects were reported.

The study at a glance

Type of study
Systematic review
Who or what was studied
11 studies, 805 people · 805 people in 11 placebo-controlled trials, covering skin aging, dry skin, pressure sores and cellulite
What was tested
Collagen by mouth, 2.5g/d to 10g/d for 8 to 24 weeks, compared with placebo
What it measured
The question itself: skin wrinkles, elasticity and hydration
Daily amount
10 g a day
How long
24 weeks
Who has a stake
No disclosure in PubMed
No disclosure in PubMed.
Journal
Journal of drugs in dermatology : JDD, 2019
Source
PubMed record 30681787. This page is based on the abstract only.

How much this study counts

  • •Sums up 11 studies found with a set search method, without pooling the numbers.
  • ✓Measured the question itself: skin wrinkles, elasticity and hydration.
  • •The PubMed record has no conflict-of-interest statement.
  • •Summarized from the PubMed abstract only. The full paper may hold details the abstract leaves out.

✓ Strength– Limit• Note

These points come from fixed rules about the type of study, its size and length, what it measured, and who has a stake. Every study on Digestery gets the same rules.

Where this study sits

This paper is not on the ladder. It is a systematic review, and reviews and opinion pieces discuss studies that are already counted on the steps below.

↑ Stronger evidence

  1. Trials in people: wrinkles, skin elasticity and moisture

    15

    13 benefit, 2 mixed

  2. Trials in people: other measures

    1

    1 benefit

  3. Trials in people: lab tests or safety

    0

    None among the papers we read.

  4. Population studies

    0

    None among the papers we read.

  5. Blood levels and genes

    0

    None among the papers we read.

↓ Weaker evidence

  • Points to benefit
  • Mixed
  • No difference
  • No direction
  • Points to harm

How it fits with the other research

The short answer to “Does collagen reduce skin aging?”

Unclear; higher-quality trials found no effect.

Confidence: low. Based on 22 on-topic papers.

Read the full answer

Other reviews on this question

See all 22 studies on this question

How this page was made

Label

First read of the abstract
Claude Sonnet
Independent second read
Claude Haiku
Differences settled
The reviewer corrected 1 field after reading the abstract. Claude Opus 5.5.
Headline
Claude Sonnet, from the checked study record. A script checked its numbers and wording.
Numbers
Checked against the abstract by a script
“How much this study counts”
Fixed rules, the same for every study
Source check by a person
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