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Longevity supplements › Resveratrol and Aging › Studies

Randomized trial · measured the question itself

90-day trial in 32 older adults: resveratrol improved one thinking test, not others

Anton and colleagues · Journal of alternative and complementary medicine (New York, N.Y.) · 2018

Original title: Effects of 90 Days of Resveratrol Supplementation on Cognitive Function in Elders: A Pilot Study.

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What the study found

Mixed

Speed on one test, Trail Making part A, improved on 1000 mg/day vs 300 mg and placebo (p = 0.02). Other thinking skills did not change significantly.

The study at a glance

Type of study
Randomized trial
Who or what was studied
32 people · Overweight, inactive adults aged 65 to 93
What was tested
Resveratrol 300 mg a day or 1000 mg a day vs placebo for 90 days
What it measured
The question itself: aging and age-related disease
Daily amount
1000 mg a day
How long
13 weeks
Who has a stake
Company stake
Dr. Anton was a scientific advisor and consultant for Reserveage Organics, which made the resveratrol used.
Journal
Journal of alternative and complementary medicine (New York, N.Y.), 2018
Source
PubMed record 29583015. This page is based on the abstract only.

How much this study counts

  • ✓Randomized: people were put into groups by chance, so the groups start out alike.
  • ✓Compared with a placebo, a dummy treatment.
  • –Small: 32 people. Small trials can miss real effects or find chance ones.
  • •Lasted 13 weeks.
  • ✓Measured the question itself: aging and age-related disease.
  • –Company stake: Dr. Anton was a scientific advisor and consultant for Reserveage Organics, which made the resveratrol used.
  • •Summarized from the PubMed abstract only. The full paper may hold details the abstract leaves out.

✓ Strength– Limit• Note

These points come from fixed rules about the type of study, its size and length, what it measured, and who has a stake. Every study on Digestery gets the same rules.

Where this study sits

Each dot is one on-topic paper on this question. Steps near the top answer the question more directly.

↑ Stronger evidence

  1. Trials in people: aging and age-related decline

    3

    1 benefit, 1 mixed, 1 no difference

    ↑ This study is the ringed dot

  2. Trials in people: other measures

    3

    1 benefit, 1 mixed, 1 harm

  3. Trials in people: lab tests or safety

    7

    4 benefit, 2 mixed, 1 no difference

  4. Population studies

    1

    1 benefit

  5. Blood levels and genes

    1

    1 no difference

  6. Animals

    1

    1 benefit

↓ Weaker evidence

  • Points to benefit
  • Mixed
  • No difference
  • No direction
  • Points to harm

How it fits with the other research

The short answer to “Does resveratrol slow aging?”

Not shown in people.

Confidence: very low. Based on 22 on-topic papers.

Read the full answer

Of the other 2 papers on the same step: 1 benefit, 1 no difference. This one found mixed.

Other papers on the same step

See all 22 studies on this question

How this page was made

Label

First read of the abstract
Claude Sonnet
Independent second read
Claude Haiku
Differences settled
The two reads agreed on every checked field. Claude Opus 5.5.
Headline
Claude Sonnet, from the checked study record. A script checked its numbers and wording.
Numbers
Checked against the abstract by a script
“How much this study counts”
Fixed rules, the same for every study
Source check by a person
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